Institute of Molecular Biology


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Raghuveer Parthasarathy

Raghuveer Parthasarathy

Associate Professor, Physics
Associate Member, IMB

Ph.D., University of Chicago
B.A., UC Berkeley

Email
Lab website
Office: Willamette Hall Room 362
Office Phone: 441-346-2933

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Research Interests

The Parthasarathy lab constructs experiments that explore a variety of topics in biophysics, focusing especially on the physical properties of membranes. Recent work has examined, for example, the mechanisms by which intracellular trafficking proteins may sculpt organelle membranes and the peculiar fluid dynamics of lipid bilayers. We also develop imaging and image analysis tools that enable these sorts of studies. See our lab webpage for more information.

Recent publications

(pulled from pubmed)

Recent publications

(pulled from pubmed)

A Bright Fluorescent Probe for H2S Enables Analyte-Responsive, 3D Imaging in Live Zebrafish Using Light Sheet Fluorescence Microscopy.
Hammers MD, Taormina MJ, Cerda MM, Montoya LA, Seidenkranz DT, Parthasarathy R, Pluth MD
J Am Chem Soc 2015 Aug 19;137(32):10216-23
Two-Point Microrheology of Phase-Separated Domains in Lipid Bilayers.
Hormel TT, Reyer MA, Parthasarathy R
Biophys J 2015 Aug 18;109(4):732-6
Ballistic and diffusive dynamics in a two-dimensional ideal gas of macroscopic chaotic Faraday waves.
Welch KJ, Hastings-Hauss I, Parthasarathy R, Corwin EI
Phys Rev E Stat Nonlin Soft Matter Phys 2014 Apr;89(4):042143
Measuring lipid membrane viscosity using rotational and translational probe diffusion.
Hormel TT, Kurihara SQ, Brennan MK, Wozniak MC, Parthasarathy R
Phys Rev Lett 2014 May 9;112(18):188101
Spatial and temporal features of the growth of a bacterial species colonizing the zebrafish gut.
Jemielita M, Taormina MJ, Burns AR, Hampton JS, Rolig AS, Guillemin K, Parthasarathy R
MBio 2014 Dec 16;5(6)
Comparing phototoxicity during the development of a zebrafish craniofacial bone using confocal and light sheet fluorescence microscopy techniques.
Jemielita M, Taormina MJ, Delaurier A, Kimmel CB, Parthasarathy R
J Biophotonics 2013 Dec;6(11-12):920-8
Robust measurement of membrane bending moduli using light sheet fluorescence imaging of vesicle fluctuations.
Loftus AF, Noreng S, Hsieh VL, Parthasarathy R
Langmuir 2013 Nov 26;29(47):14588-94
Structure and proposed mechanism for the pH-sensing Helicobacter pylori chemoreceptor TlpB.
Goers Sweeney E, Henderson JN, Goers J, Wreden C, Hicks KG, Foster JK, Parthasarathy R, Remington SJ, Guillemin K
Structure 2012 Jul 3;20(7):1177-88
Modulation of membrane rigidity by the human vesicle trafficking proteins Sar1A and Sar1B.
Loftus AF, Hsieh VL, Parthasarathy R
Biochem Biophys Res Commun 2012 Oct 5;426(4):585-9
Investigating bacterial-animal symbioses with light sheet microscopy.
Taormina MJ, Jemielita M, Stephens WZ, Burns AR, Troll JV, Parthasarathy R, Guillemin K
Biol Bull 2012 Aug;223(1):7-20
A greasy foothold for Helicobacter pylori.
Wandler AM, Parthasarathy R, Guillemin K
Cell Host Microbe 2010 May 20;7(5):338-9
The vesicle trafficking protein Sar1 lowers lipid membrane rigidity.
Settles EI, Loftus AF, McKeown AN, Parthasarathy R
Biophys J 2010 Sep 8;99(5):1539-45
Phospholipid bilayers are viscoelastic.
Harland CW, Bradley MJ, Parthasarathy R
Proc Natl Acad Sci U S A 2010 Nov 9;107(45):19146-50
Synthetic trehalose glycolipids confer desiccation resistance to supported lipid monolayers.
Harland CW, Botyanszki Z, Rabuka D, Bertozzi CR, Parthasarathy R
Langmuir 2009 May 5;25(9):5193-8